
efficacy of a Weight Loss Program Using Digital Health in Adolescents and Preadolescents
Sha Lei
1Department of Cardiovascular Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
2Department of Cardiology, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.
Jose R. Medina Inojosa
1Department of Cardiovascular Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Seema Kumar
3Division of Pediatric Endocrinology and Metabolism, Department of Pediatric and Adolescent Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Alexander T. Lee
4Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN, USA.
Christopher G. Scott
4Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN, USA.
Amir Lerman
1Department of Cardiovascular Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Lilach O. Lerman
5Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Conor G. Senecal
1Department of Cardiovascular Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Weihua Lin
6Hangzhou MetaWell Technology Co., Hangzhou, China.
Xiaoyong Zhang
6Hangzhou MetaWell Technology Co., Hangzhou, China.
Pinchas Cohen
7USC Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Francisco Lopez-Jimenez
1Department of Cardiovascular Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Abstract
Objective: To pick out an efficacious intervention on treating adolescents with obese and obesity, this might result in health advantages.
Methods: Adolescents with obese or obesity aged 10–17 years with BMI percentile ≥85th have been blanketed on this ancient observational evaluation. Subjects used a completely far off eating regimen combining mobile applications, frequent self-weighing, and calorie restrict with meal alternative. Body weight changes were evaluated at forty two, 60, ninety, and a hundred and twenty days the use of special metrics such as absolute frame weight, BMI, and BMI z-score. Chi-rectangular or Fisher genuine checks (express variables) and Student's t-check (non-stop variables) were used to evaluate subjects.
Results: In general, 2,825 contributors, suggest age 14.4 ± 2.2 years, (54.Eight% ladies), have been included from October 27, 2016, to December 31, 2017, in mainland China; 1355 (48.0%) had a baseline BMI percentile ≥97th. Mean BMI and BMI z-score were 29.20 ± four.Forty four kg/m2 and 1.89 ± 0.Forty two, respectively. At day one hundred twenty, suggest discount in body weight, BMI, and BMI z-score changed into eight.6 ± zero.63 kg, three.Thirteen ± 0.21 kg/m2, and zero.Forty two ± 0.03; seventy one.Four% had lost ≥five% body weight, sixty nine.4% of boys and 73.2% of women, respectively. Compared with boys, girls executed greater discount on BMI z-rating at all periods (p < zero.004 for all comparisons). Higher BMI percentile at baseline and increased frequency of use of the cellular application have been without delay related to more good sized weight reduction
Conclusions: An totally far flung digital weight loss plan is powerful in facilitating weight reduction in adolescents with obese or weight problems in the quick time period and mid term.@ Read More clubhitech
Introduction
The prevalence of obese and weight problems amongst youth has increased unexpectedly in both advanced and developing international locations, giving upward push to severe global public health difficulty.1–three Growing proof shows that teenagers with obese or weight problems face psychosocial and physical challenges on account of their excess weight,four–7 and are much more likely to be afflicted by mental disorders, bullying, and discrimination than normal weight friends.Four,6 Importantly, overweight and obesity are associated with persistent fitness consequences including type 2 diabetes mellitus, dyslipidemia, hypertension, allergies, and different comorbidities.Five,8,9 In addition, adolescents with obese or obesity are more likely to stand multiplied fitness dangers in maturity than people of healthful weight of their young people.10–12 Most of the aforementioned factors boom the threat of cardiovascular diseases, contributing to population burden of sickness through impacting morbidity and all-cause mortality.2,13,14
Because modest weight loss can drastically lessen cardiovascular danger,15–17 several effective way of life intervention applications had been developed to combat obesity amongst youngsters.18–20 Protocols specializing in accomplishing changes in food regimen and bodily pastime look like powerful strategies of weight reduction and behavior management in teens with obese or weight problems.18–20 However, those present day life-style interventions have confirmed to be useless in weight reduction or long-time period preservation,19,21 developing the need to complement conventional techniques with evidence-primarily based programs that yielded extra efficacy. The software of remote technology for weight management is an area of great innovation and capacity that might possibly be especially attractive for adolescents who're already so nicely related with mobile devices and social media systems. Use of far off era which include mobile phones is pervasive amongst young people and had been examined in several weight loss programs for this populace.21
Limited paintings has shown promising outcomes using these technologies to promote and gain weight reduction,22,23 as digital techniques can overcome limitations along with access, location, and cost in weight management programs a few of the preadolescent and adolescent-age businesses. Considering that the majority of research using digital technology have been performed in adults and have been limited by means of small pattern sizes and heterogeneity of techniques, similarly research in teenagers the usage of promising intervention and huge populations is required to determine the impact of those tools on weight problems control.@ Read More stylebeautyonline
The purpose of this study become to evaluate the efficacy of a virtual health platform for weight reduction making use of a cellular software, a wireless scale and calorie restriction with nutritional supplementation in a big retrospective observational look at in adolescents.
Methods
The MetaWell faraway weight loss plan ($770; Weijian Technologies, Inc., Hangzhou, China) is a wholly far flung software, with none form of face-to-face interplay. The program includes a loose cellular software to be had on each Apple® and Google Play® app stores mixed with a wireless domestic scale (Senhe Industrial, Co., Ltd., Shenzhen, China) as well as a nutrients software. Upon down load of the cell utility, customers had been precipitated to sign up, provide age, gender, and other simple demographic facts (Supplementary Appendix SA1). Participants had been additionally brought on to buy the associated wireless ($forty five) scale that captured frame weight.
The nutrients software was tailor-made primarily based on each participant's basal metabolic requirements (BMRs) anticipated with the aid of Schofield's predictive equation (kcal/day) as cautioned via FAO/WHO/UNU24: For boys elderly 10–18 years: BMR = 650 + 17.5W, whereas for women: BMR = 743 + 12.2W, in which W represents body weight in kilograms. The recommendation become to attention on ingesting a food regimen of all food corporations even as recommending a bad calorie balance of 30%, which means a calorie intake equal to 70% of their predicted daily calorie expenditure. Participants have been provided individualized low-calorie meal plans that consisted of wholesome recipes delivered through the cell software, supplemented with up to a few daily Yufit® biscuits (low calorie 416 kcal/100 g, 11.2 g of protein/100 g, and noncaffeinated meal replacements with a low glycemic index). Participants had been given nutritional facts in addition to sample nutritional plans (Supplementary Appendix SA2). Direct measures of complement usage during the time period studied were unavailable.@ Read More cosmopolitansblog
Once members had achieved target weight (i.E., both a 10% loss of baseline weight or a weight percentile <eighty fifth percentile), a transition diet regime changed into advocated. Participants and their dad and mom have been informed to degree urinary awareness of ketones every morning, with ketones suggested on a scale from 0 (0 mg/dL) which means no ketosis to 4 (one hundred sixty mg/dL) meaning potentially risky ketosis, with a purpose of 2 (forty mg/dL) to a few (eighty mg/dL) levels. An boom in carbohydrate consumption changed into advocated if ketone size turned into at level 4 at any time point. If three consecutive measurements of stage 4 were observed, the user changed into advocated to prevent the plan and consume a better carbohydrate weight loss plan.
Physical hobby turned into advocated all through this system, however no precise workout suggestions had been provided. Users have been caused with the aid of the software to weigh themselves on a daily basis via the wireless scale. In the application, contributors had get admission to to a document of their weight reduction progress, in addition to a “Health Status Overview” that supplied a photo in their modern-day fitness data as well as choicest measures of BMI. Screen captures of the software are offered in Supplementary Appendix SA1.
Study Protocol
We blanketed topics aged 10 to 17 years who completed the economic MetaWell application in mainland China from October 27, 2016, to December 31, 2017, and subjects have been expected to have not less than recorded participations together with measurements at baseline weight and at 35 days or past (evaluation of folks that had <35 days, Supplementary Appendix SA3), in addition to a baseline gender- and age-unique BMI ≥85th percentile using the BMI tables from the Center of Disease Control.24@ Raed More foxconnblog